Two comedies battled for box office supremacy this Easter weekend and the interracial romantic comedy “Guess Who,” starring Ashton Kutcher and Bernie Mac, handily defeated “Miss Congeniality 2: Armed and Fabulous,” starring Sandra Bullock.

The first pairing of Ashton Kutcher and Bernie Mac proved successful as “Guess Who” took first place at the box office by grossing an estimated $21M this weekend. This marked a personal best for Ashton Kutcher for films in which he has top billing. His previous best was another romantic comedy, “Just Married,” which debuted with $17.5M in 2003. Of the two new wide releases this weekend, it was the better reviewed with 43% on the Tomatomter. Despite the chemistry of its stars, critics thought “Guess Who,” a loose remake of “Guess Who's Coming to Dinner,” lacked the political relevance of the original.

In 2nd place was “Miss Congeniality 2: Armed and Fabulous,” the sequel to one of Sandra Bullock’s most successful films. It did an estimated $14.5M in business this weekend. Since opening on Thursday, it has grossed $17.6M. “Miss Congeniality 2’”s $14.5M opening is slightly better than the original’s $13.9M debut, which ended its theatrical run with an impressive $106.8M. With almost universally bad reviews at 19% on the Tomatometer, the sequel would be lucky if it can finish with half of the original’s total. Critics thought Sandra Bullock was still as appealing as ever; too bad the movie was not pageant material.

Last weekend’s first place finisher “The Ring Two” dropped to 3rd with an estimated $13.8M, a staggering 61% drop-off from the previous weekend. It has grossed $58M after two weeks of release.

“Robots” placed 4th with an estimated $13M. Its total after three weeks of releases is $87.4M.

“The Pacifier” continues to do strong business. It did an estimated $8.5M in business and placed 5th. Its total after four weeks of release is $86.2M.

Rounding out the rest of the top 12 are “Hitch” in 6th with $4.3M ($166.5M total), “Hostage” in 7th with $4.1M ($26.2M total), “Ice Princess” in 8th with $3.7M ($13.3M total), “Be Cool” in 9th with $2.9M ($52.4M total), “Million Dollar Baby” in 10th with $2.6M ($94.6M total), “The Upside of Anger” in 11th with $1.3M ($4M total), and “Constantine” in 12th with $1.2M ($72.7M total).

Click here for the detailed chart.